RESEARCH PARK OF UZHHOROD NATIONAL UNIVERSITY: INTRODUCTION AND INNOVATIVE POTENTIAL IN CURRENT FP7 CALLS Ihor Studenyak, Yosyp Golovach Uzhhorod National. - презентация

1 RESEARCH PARK OF UZHHOROD NATIONAL UNIVERSITY: INTRODUCTION AND INNOVATIVE POTENTIAL IN CURRENT FP7 CALLS Ihor Studenyak, Yosyp Golovach Uzhhorod National University, Uzhhorod, Ukraine

2 The state higher educational institution of the IV accreditation level; The Ministry of Education and Science of Ukraine Licence AB ; Year of establishment – 1945; Number of faculties – 18; Number of students –12000 students; Forms of studies: day-time, extra-mural, continuing post diploma studies on the state budget funding and on the contract basis. 1.General information about Uzhhorod National University

3 Educational qualification levels: the Bachelor's, the Specialist's, the Master's programs. Number of professors, Doctors of Sciences – 105; Number of Associate Professors, Candidates of Sciences – 450; Number of Honoured Workers of Science and Technology, Honoured Educationalists, Physicians, Inventors – over 50. Post graduate courses, preparatory department and preparatory courses, Refresher courses. The University maintains international cooperation with 62 higher educational establishments of the world. University Address: 46, Pidhirna St., Uzhhorod, Ukraine, Rector's office: 46, Pidhirna St., Uzhhorod, Ukraine, Tel/ Fax. 38 (03122) , ; Tel. 38 (03122) Web-site:

4 The R&D of Uzhhorod National University is aimed at performing the fundamental and applied research projects in the priority directions of the development of science and technology, at the support, development and effective use of the University's R&D potential, at training high quality scientific and pedagogical staff, at increasing the teaching and educational process standards level at the integration of the education and science in the context of the Bologna process major guidelines, officially acceded to by Ukraine.

5 Institute of Carpathian Studies The institute was created in Institute performed fundamental and applied research directed at: the study of history, archaeology, ethnography, history of art of Transcarpathian region in its interconnection with the Carpathians region the development of practical recommendations in ethno- political and ethno-social questions the research of history of Ukrainian diaspora in Europe and America the development of regional manuals for the educational network of Transcarpathian region

6 Institute of Solid State Physics and Chemistry The Institute was founded in 1992 on the basis of Problem research laboratory for synthesis and research of complex semiconductor compounds. The basic directions of its activities are: the physics of phase transitions and critical phenomena in multi- component structures; the technology of preparation of new crystalline, glassy and thin-film functional materials; the primary transformers and functional elements for the detectors of optical, thermal and acoustic radiation; the optolectronic systems of registration and information treatment.

7 Institute of State Administration and Regional Development The institute was created in1997. The basic directions of its activities are: the elaboration of the programs for qualification increasing and preparation of public servants in different categories; the organization of educational courses; the consultative, expert, informatively technical assistance to the organs of state administration, local self-government, public organizations, business structures; the conducting of research for state administration, regional policy and development, local self-government.

8 Institute of Brain The Institute was created in The Institute executes fundamental and applied research directed at: the improvement of diagnostics and treatment of vascular diseases of brain and spinal cord; the study of possibilities of epilepsy surgical treatment; the treatment of pain syndromes; the complex research of infectious-inflammatory, immune and degenerative nervous diseases; the treatment of new pharmacology of the nervous system; the improvement of intensive therapy for patients with lesion of nervous system; the study of new methods of surgical treatment of patients with lesion of nervous system.

9 Institute of Ukrainian Studies The Institute of Ukrainian Studies was founded in The basic directions of scientific and practical activities are: the complex research of problems of Ukrainian history, political science, sociology, language, literature, folklore; the realization of direct contacts and joint scientific research with Ukraine- directed scientific - pedagogical, scientific and scientific-educational institutions of neighboring countries (Slovakia, Romania, Serbia, Poland, the Czech Republic); the organization of dialectology and folklore expeditions for the research of Ukrainian ethnographic acres and places of compact residence of Ukrainians.

10 Institute of Phytotherapy The Institute was created in The main directions of its activities are: the development of phytopreparations for the prevention and treatment of patients with internal organs pathology, caused by small doses of ionizing radiation influence; the issue of developed phytopreparations and phytoproducts; the development of computer expert systems of diagnostics, prognostication and optimal phytotherapy; the development of new instrumental diagnostic methods of pre-tumour and tumour states.

11 Institute of Analytical Technique The Institute created in The basic directions of its activities are: the implementation of fundamental, scientific-research, research-design, scientific-industrial works and services; the development of new element base of machine-building with the application of microelectronic technologies; the development of analytical devices among which there are devices of gas analysis for the control and protection of environment, for the special technological processes of labour protection, accident prevention; the production and realization of research models of scientific and technical production, elaboration of technical documentation for mass-production.

12 Laboratory of Physical Electronics with Space Research Department The Laboratory, opened in 1965, was the first scientific institution at the university. The Laboratory include: - The department of emission electronics is the research of conformities and mechanisms of the phenomena of emissions at the irradiation of the surface of solids and tapes by ions, electrons and photons. - The department of quantum electronics studies physics processes in plasma of high pressure gas lasers on excimer and other molecules.

13 - The department of electron-atomic collisions deals the research of processes of inelastic со-оperations of electrons with the normal and metastable atoms of metals, and also with the molecules of nucleic acids and metalhalogenides. - The department of space research conducts the observation of artificial and natural space bodies, research of surrounding space.

14 Laboratory of Natural Ecosystems Safety The Laboratory was created in The basic directions of its activities are: the forming of computer data bank of the naturе protected fund of Transcarpamian region and development of its perspective network: the research and inventory of flora and fauna of the nature protected territories; the creation of the computer data bank of these types of flora and fauna of Transcarpathian region, brought to the Red Book of Ukraine, and also those that are the under the threat of their disappearance; the monitoring research of bioecological features of the population of most imgressionable rareand vanishing types of plants and animals.

15 Hungarology Center The Hungarology Center of Uzhhorod National University was founded in The basic directions of its scientific research are: Ukrainian-Hungarian interlingual (interdialectal) contacts; interliterary and interethnic communications; Hungarian dialects of Transcarpathian region and linguogeography.

16 Center of Family Medicine The Center was created in The aim and functions of the Centre are: the providing of studies of interns and students of appropriate specialities; the scientific describing and providing of target clinical examination; the introduction of clinical protocols of diagnostics and treatment, the improvement of medical service quality; the co-ordination of work for stage-by-stage introduction of family medicine the region; the development, edition and realization of educational and methodical materials for students, interns and doctors; the conducting of scientific research, experimental and inculcating research in the field of information and telecommunication technologies in the system of education and health protection.

17 Center for the Trial of New Medications The center was created in 2005 with the purpose of development of new methods of treatment of patients with oncologic pathology, elaboration and introduction into clinical practice of new schemes and modes of chemotherapy of malignant neoplasm. The basic directions of its activities are: the trial of newantitumoral medication of domestic and foreign production; the research of new combinations of known medications, used in oncology, and also in studying of the mechanisms of tumour resistance to chemopreparations.

18 2. The Research Park of Uzhhorod National University Legal, economic, organizational relations are regulated by the Law of Ukraine "On research parks" N 1563-VI of June 25, A Research Park is created to develop the scientific, technical and innovative activity in a higher educational establishment and/or scientific institution, ensure efficient and rational use of the existing scientific potential and the material and technical base for the commercialization of research results and their implementation on the domestic and foreign markets. Functions of the Research Park are the following: creation of new kinds of innovative product; promotion of development and support of small innovative business; support of high-technology production; development of international and domestic cooperation in science, technology and innovation, promoting of foreign investment.

19 Priority directions of the Research Park activity The list of the priority directions of the Research Park activity is formed according to the Laws of Ukraine "On the priority directions of science and technology development" ( ) and "On the priority directions of innovation activity in Ukraine"(433-15) in compliance with the directions of research activity of higher educational establishment and/or scientific institution to meet the needs of the region (territory), where the Research Park is located. The list of the Research Park priority directions of activity is adopted by authorized central body of executive power in the field of science, technology and innovation at the approval of decision to create the Research Park. Government order for the Research Park on products supplying Applications of the scientific parks to receive government orders to supply products, perform works and render services for top- priority needs of the state are reviewed on a priority basis Performing of government orders is subject to contractual basis in the manner determined by the Law.

20 Normative base Law of Ukraine 523-V "On the Research Park Kyivska Politekhnika of Cabinet of Ministers of Ukraine 546-r "On the approved plan to implement the Law of Ukraine" On the Research park "Kyivska Politekhnika" of Order of the Cabinet of Ministers of Ukraine 760-p "On approval of innovative program of the Research park "Kyivska Politekhnika" for of The Law of Ukraine 1563-VI "On the Research Parks" of June 25, 2009 The Research Parks Projects: - developed on a competitive basis within the priority directions of activity taking into account the requirements of the Laws of Ukraine "On innovation activity", "On state regulation of activities in technology transfer", "On special regime of innovative activity of technological parks;

21 - projects are submitted to the executive management body under the terms of the competitive tenders concerning implementation of the Research Parks priority directions. By the results of tender the executive authority of the Research Parks management makes a decision about implementation of the project and concludes an agreement of partnership; - registration of all the projects of the Research Park, at realization of which is signed an agreement of partnership, is carried out by the executive authority of the science parks management; - projects, which implementation will require state support are subject to state registration by the Cabinet of Ministers of Ukraine. The Research Park of Uzhhorod National University In accordance with the Law of Ukraine "On Research Parks" in Transcarpathian region has been started an active process of the Research Park creating. In accordance with the decision of the Joint meeting of the Conference of the staff and the Academic Board of Uzhhorod National University on August 31, 2009 the work on the establishment of the Research Park was initiated.

22 Structure of the Research Park of Uzhhorod National University STATE GOVERNMEN T LOCAL GOVERNMEN T INSTITUTING OF INNOVATIVE PRODUCTS ON DOMESTIC AND FOREIGN MARKETS BUSSINESS NATIONAL AND FOREIGN COMPANIES INNOVATIVE BUSINESS INCUBATOR UNIVERSITY RESEARCHPARK INVESTMENT COMPANIES, VENTURE AND OTHER FUNDS SCIENTIFIC AND EDUCATIONAL SUBDIVISIONS

23 The priorities of innovational activity of Research Park at Uzhhorod National University In accordance with the Law of Ukraine The priority of innovational activities in Ukraine the main priorities of innovational activity for Research Park are determined: new and renewable power sources; newest resource-saving technologies; machine building and instrument engineering as the basis of high- technology update of all industrial branches; nanotechnologies, microelectronics, informational technologies, telecommunications; improvement of chemical technologies, new materials, development of biotechnologies; high-technology development of agriculture and remanufacturing industry; public health care, health improvement and environmental protection; development of innovational culture of society.

24 3. Innovation program of Uzhhorod National University Research Park The present Innovation Program of Uzhhorod National University Research Park is aimed support of constant improvement of the socio- economic balance of Transcarpathian region by implementation of new efficient forms of innovation and investment cooperation of the scientific and technological elite, business and financial community, regional power and local communities with the use of own power, natural, technological, logistic and staff resources, as well as the scientific and technological potential of the Research Parks participants. This Innovation Program will enable to detect and initiate the influential projects that are of primary importance for the improvement of the regions socio-economic development, and of the innovation activity in the regional industrial system.

25 New and renewable power sources The issues of the development of the energy sector and launch of the latest alternative technologies are to be solved simultaneously in several directions. Within the process, the following projects are to be implemented: efficient launch of alternative technologies in the industrial, municipal and private sectors in Transcarpathian region; introduction of alternative power sources; development of renewable power sources; introduction of ecologically efficient household and industrial waste recycling technologies; introduction of heat insulators production technology based on local raw materials and solid household waste. Implementation of the above activities will enable: to substantially decrease the consumption of natural gas and electricity in the industrial, municipal and private sectors in Transcarpathian region; to start recycling of solid household and industrial waste directly at the site of emergence; to assimilate various types of renewable power sources in practice.

26 Projects No.Project title Term of fulfillment, years Results expected 1Organization grounds for the development of an introduction cluster of energy efficient technologies and alternative sources Development of the pattern of efficient cooperation within the chain government (local authorities) – scientific, RD institutions – banking institutions – businesses – customer/consumer; efficient launch of energy-saving technologies and alternative energy sources in the industrial, municipal and private sectors of Transcarpathian region. 2Implementation of innovative energy- efficient elements (the Burner project) 2011– 2012 Substitution of the electric heating appliances used by government-financed organizations (education, health care, etc.) with new-generation power-saving appliances; savings of up to 35 – 40% of the consumed electrical power; reduction of budget allocation on electricity; increase of the efficiency and reliability of functioning of public energy sector.

27 3Implementation of programmed electric heating appliances 2011– 2015 Support of: introduction of the accounting systems based on multirate meters; alignment of the load curves in the power supply systems; savings of electricity by government-financed organizations and individual consumers (if electric heating be used in the nighttime only, the savings would make up to 60%). 4Implementation of the technology of recycling and treatment of mechanical rubber products (used automobile tires) 2012– 2014 A reliable and highly efficient means of radical solution of the problem of recycling of mechanical rubber products (automobile tires); an ecologically pure technology; the output of high-calorific energy carriers (combustible gas and black oil) and secondary raw materials (technological carbon and scrap metal). 5Implementation of the cracking technology for polymer materials – solid household and industrial waste 2013– 2014 Implementation of a principally new environmentally friendly technology able to efficiently recycle a broad spectrum of polymer waste into electric and heat energy

28 6Providing for the energy efficiency of heat-and-power engineering plants by means of introduction of gas analyzers to control and adjust the burning process 2012– 2015 On-line controlling of the heat losses emitted with exhaust gases due to incomplete combustion; maintenance of the optimum burning mode with max. efficiency; minimization of the atmospheric emissions of harmful gases (carbon< nitrogen oxides, etc.). 7Development and serial implementation of high- performance solar collectors for the regions of moderate climate (Transcarpathian region) 2012– 2015 Implementation of alternative renewable power sources into the industry of Transcarpathian region; solution of economic and ecological problems due to decrease of the consumption of hydrocarbon fuel and of emissions of greenhouse gases. 8Development of the technological process of manufacture of heat- insulated materials by recycling of mixed glass and glassware waste as part of household waste 2012– 2014 Implementation of the recycling system for mixed glassware waste as part of household waste; production of a thermo-insulating material of pinoglass type; substantial lessening of environmental pollution; resource-saving and energy conservation.

29 9Development and implementation of soil accumulators of low-grade heat energy from alternative sources 2013– 2015 Development of turnaround soil accumulators of solar energy and natural cold with the use of certain types of available and anthropogenic raw materials (e.g., zeolites); solution of the problem of accumulation and redistribution of the energy obtained from alternative sources (wind, solar, etc.).

30 Machine building and instrument engineering as the basis of high-technology update of all industrial branches A complex of activities aimed at development of competitive equipment and up-to-date technologies is to be fulfilled in the following directions: joining of the engineering and designer potential of Transcarpathian scholars and machine building and instrument engineering industries to develop and launch large-scale production of high-technology products and up-to-the-minute technologies; development of the element base for machine building and instrument engineering (semiconducting gas sensors, chemical sensors, fibre-optic biosensors, diffraction structures, etc.); development of a new generation of gas analyzers for medicine, and implementation of safe practice into industry and use of household appliances;

31 development and implementation of medical equipment (halo generation instruments as artificial counterparts of Solotvyna mines microclimate, mobile local medical waste utilizers, etc.); implementation of up-to-the-minute technologies (plasma-optical technologies for high quality water preparation systems and reagent- free disinfection of loose (granular) media; technologies to produce materials with new properties with the use of metallothermy and self- distributing high-temperature synthesis (SHS), etc.). Implementation of the above activities will be aimed at development of the national high-end technology industry for safety arrangement and precautions, medicine and domestic use, and launch of up-to-the-minute technologies; providing for the introduction of innovations developed by both national scholars and foreign participants of the Research Park.

32 Projects No.Project title Term of fulfillme nt, years Results expected Element base of machine building and instrument engineering 1Development of new- generation semi- conducting gas sensors for broad gas spectrum 2013– 2015 Development and serial production of semi-conducting gas sensors with advanced performance characteristics; development of sensor-based gas analyzers of new type. 2Development of a remote sensor of carbon oxide microconcentrations in the air of the working area 2012– 2013 Development and full-scale production of remote sensors of background values of carbon oxide meant for identification of current and mean values of carbon oxide concentration in the atmospheric air of the working areas of industrial plants, sanitary protective areas and populated areas. 3Development of fiber optic biosensors for in vivo identification of Helicobaсter pylory, and monitoring of local anesthetics concentration 2011– 2013 Development of a multisensory fiber optic system with low-invasive selective sensors based on Y-shaped microfibers, able to complete the existing gastroendoscopes and other diagnostic devices.

33 4Development of chemical sensors for identification of the biogenic elements and major environmental pollutants 2012–2014Development and launch of chemical sensors; introduction of the sensors into Automatic Test Equipments (ATEs) of biogenic elements and pollutants in food products (potable and mineral water, wines, juices), natural and industrial objects (hydrothermal and surface water, process liquors, household chemicals, etc.); simplification, improvement of reliability and reduction in price of the identification procedure for major physical and chemical parameters, pollutants and biogenic elements. 5Development of zero-level diffraction structures 2011–2012Improvement of the technical characteristics of holographic elements in document protection technologies (strict accounting documents, highly- protected excise stamps, etc.). 6Development of magnet- resonance surveying identifier of coordinate locations 2011–2016Development and serial implementation of magnet- resonance boundary identifier of coordinate locations to improve the trustworthiness level and preciseness of coordinate locations of the boundaries of surface objects: land plot boundaries, observation points in surveying, topography, cartography and construction.

34 Safety arrangement devices 7Development of new- generation domestic gas detectors meant for continuous control of methane and carbon monoxide concentrations 2011–2012Organization of the manufacture of household gas detectors of domestically produced elements Development of new-generation household gas detectors with improved technical and economic characteristics, and full-scale launch of their production. 8Development of midget optocoupler infrared gas analyzers of carbon dioxide concentrations 2012–2014Development and serial implementation of gas analyzers of carbon dioxide concentrations; public safeguarding in public and municipal premises; control of СО 2 concentrations in agricultural premises (greenhouses, farms, etc.). 9Development of multichannel indicators of toxic and explosive gases for industrial enterprises 2012–2013Development and serial implementation of multichannel indicators; improvement of the ecology and safety of industrial and municipal entities. 10Development of a gas- type fire announcer 2011–2012Development and serial implementation of a gas-type fire announcer; development of a new type of fire announcers to detect the fire at earliest possible stage.

35 11Development of individual gas analyzing kits based on semi- conducting and electrochemical sensors 2012–2015Development of industrial and household individual gas analyzing kits to keep to the safety and labour protection rules. Medical equipment 12Development of a device meant for determination of concentration of ethyl alcohol vapours in the expired air to diagnose the intoxication stage 2012–2013Development and serial implementation of mobile portable devices meant for determination of concentration of ethyl alcohol vapours in the expired air. The device is to be used by the State Automobile Inspection, trucking companies, railways, air carriers, etc., to control the drivers soberness. 13Development of an expired air analyzing device meant for the diagnosis of human organism and possible diseases 2012–2013Development and serial implementation of domestically made carbonometers based on О 2, СО, and СО 2 semi-conducting and electrochemical sensors; substantial decrease of mortality under general anesthesia; possibility to diagnose the diseases, and improve the efficiency of identification of the diseases during medical examinations.

36 14Development and implementation of halo generation instruments (artificial counterparts of Solotvyna mines microclimate) meant for halo-aerosol therapy 2011– 2012 Development and serial implementation of halo generation instruments able to reproduce the microclimate similar to that of Solotvyna mines by formation and spread of dry aerosol salt particles in aerosol therapy chambers (with adjustable particles dispersion and concentration meant for differentiated treatment of respiratory diseases). 15Introduction of mobile local recyclers of medical waste for health care institutions 2012– 2014 Ensuring of complete recycling of medical waste in situ ; decrease of waste transportation and recycling expenses; provision for ecological and bacteriological safety; possibility to obtain cheap power supply. New technologies 16Organizing the Centre for combined technologies for the production of materials with new properties with the use of metallothermy and self- distributing high- temperature synthesis (SHS) 2012– 2013 Strengthening of the tools made of carbide steel and cast carbide alloys by combination of SHS and metallometry; production of hardfaced surfaces when repairing, renewing and strengthening the details by means of SHS+metallometry combined processes.

37 17Implementation of plasma-optical technologies into high quality water preparation systems 2012–2015Plasma-optical technology will be implemented: – into high quality potable water preparation systems (hospitals and patient care institutions, childrens institutions: crèches, kindergartens, schools, etc.); – into household and industrial wastewater treatment systems. 18Development and introduction of equipment for plasma-optical technology of cold reagent-free disinfection of loose (granular) media 2011–2013Introduction of a new plasma-optical technology and techniques for cold disinfection of loose (granular) media; microbiological safeguarding of food products, including granular foods, ingredients of homeopathic, pharmacological and biomedical preparations, etc., preserving main consumer properties and biological value of the products; substantial prolongation of the shelf life of food products. 19Development of single- piece production of high- performance refuse wood choppers Economy of refuse wood logistic; recycling of refuse wood into valuable multipurpose primary material (alternative power engineering, production of wood particle boards, fibreboards, and cellulose) ecological efficiency related to recycling of the refuse wood left in cutting areas.

38 Development and implementation of biotechnologies A number of activities aimed at advancement of the qualitative indices and improvement of medical, food, and veterinary industries are to be implemented in the following directions: Implementation of the concept of rational antibiotic therapy in Transcarpathian region by rapid pathogen diagnosing, its susceptibility to antibiotics and, respectively, the needs to use them (express-chips), followed by substantiated application of a broad spectrum of bio- (microbial) preparations: pre-, pro-, and synbiotics, phages, vaccines, and serum immunoglobulins. Technological development and industrial launch of new types of functional products and beverages made of various local primary materials, etc., with bioactive components of plant and microbial origin, able to prevent (and regulate) metabolic-related diseases, especially food allergies, obesity and cardiovascular dysfunctions;

39 Implementation (production and sale) of the biopreparations developed by Uzhhorod National University (including Monosporine- PK and Bacella, registered in Ukraine, with approved specifications, and currently produced by Nyva Ltd. Agricultural Company in the Crimea), at local farms (state and privately owned), to ensure compliance of the meat products with the respective EU standards (antibiotic- and hormone-free advanced quality meat); Implementation of efficient quick tests for the monitoring (with the aim of detection) and further microbial-enzymatic recycling of pollutions in situ (SMART); Nanotechnologies in food industry – identification of nonmarketable products; Biotechnological processing of agricultural primary materials to prolong their shelf life without the use of preservatives, and with advanced organoleptic qualities (forage production).

40 Implementation of the above activities will enable: to implement the brand: Transcarpathian region As a Healthy Region in Every Respect : in ecological, food, medical, veterinary, and agricultural aspects, at cost of introduction of the below stated projects based on cheap biotechnological approaches; to decrease the number of clinical and other infections, to cut patient hospital upkeep costs, to accelerate the recovery, and to reduce the mortality index; to increase the number of healthy population (underage, able-bodied and elder age categories) in Transcarpathian region by food normalization and availability of functional products for different age categories with adjustable preventive properties; to provide the population with functional products made of local primary materials, able to prevent metabolic-related diseases; to successfully monitor the environmental conditions, and implement the biotechnological techniques of water and soil treatment and waste recycling.

41 Projects No.Project title Term of fulfillment, years Results expected Microbial biotechnologies in medicine and food industry 1Development and offer of new, absolutely safe and efficient medical microbial preparations with high level of specific properties, for prevention of infectious (primarily, bacterial) diseases 2011–2013Implementation of the following strategy in Transcar­ pa­thian region: the aim is safe prevention and treatment (rational – controlled – antibiotic therapy, and safe vaccination). Reasonable application of biopreparations: pre-, pro-, symbiotic, and other efficient and safe preparations: 1)Chips for pathogen identification and antibiotic susceptibility quick tests; 2)Bacteria and bacterial derivatives, their antigens as components of mono- and poly-component vaccines against agents of bacterial infections 3)Oral and nasal vaccine preparations (the so-called target vaccines).

42 2Determinative food and bacterial antigens in prevention of diseases caused by violations of immune-metabolic processes of the human organism 2011–2013New biopreparations based on selected commensal bacteria and food antigens to prevent allergies, metabolic and immune disturbances and thereby caused processes, including cardiovascular diseases 3Immune-modulating role of the commensal microbiota: new mechanisms, potential target cells, and use prospects 2013–2015New approaches to the development of domestic highly specific vaccine preparations based on preliminarily studied bacterial antigens.

43 Microbial biotechnologies in pollution monitoring and environmental protection 4Launch of the quick methods of environmental pollutions monitoring: implementation of SMART technologies for continuous tracing and identification of critical pollutions of the environmental constituents (air, water and soil) 2011–2012Continuous monitoring of potentially polluted land plots in Transcarpathian region, primarily of the water basin (detection of heavy metals, cyanides, etc.); dumps and soils from the working wood- chemical industries. 1) Microbial bioindicators and test-systems; 2) Complex (biochemical) diagnostic systems to analyze the situation in situ. 5Upgrading and launch of water treatment and preparation technologies for different industries. Treatment of soils and subterraneous waters against industrial pollutants, including phenols Launch of safe complex microbiological, biotechnological and biochemical water treatment systems of enterprises and urban canals, increase of water quality and a 10% decrease of water consumption in the new treatment systems.

44 6Launch of complex techno­lo­gical lines on recycling of hou­se­hold and industrial waste with the help of microbial preparations 2011–2015Organization of modular production plant to recycle household and industrial wastes; a 20% cut in natural gas expenditure, and a 30% cut in electricity consumption Microbial biotechnologies in agriculture, processing and food industries 7Quick indication of spoiling of raw food and food products, microbial biotechnologies in prolongation of the shelf life and improvement of the quality of the primary products for fodder and food industries 2011–2015Implementation of the system of detection of spoiled food products and methods of preliminary processing of the primary products meant to provide for its longer shelf life and quality improvement: 1)detectors of toxins and pathogenic microorganisms in food products; 2)microbial ferments.

45 8Launch of a broad spectrum of the new-line bioproducts in Transcarpathian region: fodder additives and biopreparations for veterinary (with the use of modern approaches of microbial biotechnologies) 2011– 2012 Fulfillment of the strategy in Transcarpathian region: ecologically friendly plant growing and cattle farming (the concept of organic farming) 1)Single-component - Monosporyn; 2)Composite - Bacel; 3)New strain-based (10 cultures) compositions (mixtures); the strains selected by their useful properties as deposited at Ukraines Industrial Collections (Deposit Certificates issued by Institute of Microbiology and Virology of National Academy of Science of Ukraine (IMV NASU), and State Control Institute of Biotechnology and Microbial Strains (SCIBMS)); 4)Micro- and macro-nutrients; 5)Biosorbents. 9Proposal of the new types of food products, typical for the Transcarpathian region with distinguished regulatory properties, correction of most dangerous non- infectious diseases (related with metabolic disturbance) 2011– 2013 Fulfillment of the strategy in Transcarpathian region: Healthy Food for Long Healthy Life. 1)New functional food products and beverages. Experimental samples – a new line of food products. 2)New educational approaches – a multistage comprehensive education required for the Concept to succeed.

46 10Continuous use of bioactive (plant) components of the traditional food products of the Black Sea countries 2011–2012Foundation of an international association by joint efforts of the science, industry and other interested parties, to use the newest developments and opportunities to solve the following social, ecological and economic problems: rise in demand on safer and healthier food, higher quality of the food products, and stable manufacture and use of the available traditional and new biological resources.

47 Health The following activities aimed at public health care and health improvement are to be implemented in the following directions: introduction in Transcarpathian region of early diagnosing, urgent treatment, rehabilitation and prevention of certain widely spread diseases (acute myocardial infarction, post-ischemic stroke, epilepsy, HIV-infection, etc.); efficacious prevention and correction of iodine deficiency; decrease of underage iodine endemia in Transcarpathian region based on efficient domestically produced polyfunctioning iodine-containing health-improving food additives studied at the Institute of Phytotherapy and other Uzhhorod National Universitys departments ( Lamidan, Iodis- Concentrate, etc.); prevention of endoecological diseases related with floods and other exoecological harmful factors, wit the use of phyto-teas with cleaning, immune-stimulating, cardioprotective and general health-improving activity developed and introduced by Uzhhorod National University both for the underage and adult population of Transcarpathian region;

48 use of artificial counterparts of the natural factors of highly mineralized Solotvyna Salt Lake by organization of manufacture of halophilic bacteria-based preparations to treat chronic dermatoses (psoriasis, etc.). Implementation of the above activities will enable: to cut drastically disability and mortality among the population of Transcarpathian region caused by most dangerous cardiovascular, cerebrovascular, etc. diseases; to improve the life quality and icrease the number of healthy population (underage, able-bodied and elder age categories) in Transcarpathian region by availability of functional health improvement natural means for different age categories with preventive, rehabilitation and therapeutic properties; to provide the population with affordable domestically produced natural phyto-products able to prevent ecology-related diseases.

49 Projects No.Project title Term of fulfillment, years Results expected 1Implementation of early revasculization of coronary arteries of the patients suffering from acute myocardial infarction, in Transcarpathian region 2012–2013Prevention of initiation of myocardial infarction; substantial decrease of the patients stay in hospital (to 4 – 6 days). 2Formation of a mobile team for diagnosing and treatment of epilepsy, neuromuscular apparatus, and comas of unknown etiology 2012–2013Possibility of diagnosing epilepsy, neuromuscular apparatus, and comas of unknown etiology in remote areas of Transcarpathian region.

50 3Introduction of the developments of early rehabilitation (during the first several days) and neuropsychological examination of the post- ischemic stroke patients 2014– 2015 Favouring the efficient renewal of the patients movement functions and their psychosocial adaptation (currently no early rehabilitation of stroke patients or neuropsychological examination is carried out). 4Launch of HIV infection / AIDS primary prophylactics among certain sections of the population of Transcarpathian region 2012– 2015 Development of the expanded program of preventive measures for certain sections of the population of Transcarpathian region taking into account their education level, social mentality, life conditions, etc.; development of the structure of information background of HIV infection / AIDS primary prophylactics among different sections of the population; development of curricula and programs for the regional educational and methodological institutions. 5Elimination of iodine endemic in the population of Transcarpathian region through the production of bakery products enriched with iodized protein 2011– 2015 Implementation of the regional target program "Iodine buns - Children of Transcarpathia; elimination of iodine endemic among the population of Transcarpathian region through the production of bakery products enriched with iodized protein

51 6Substantiated prevention of iodine deficiency among Transcarpathian schoolchildren 2011– 2015 Efficient correction and prevention of iodine deficiency by the use of natural iodine-containing polyfunctioning food additives for schoolchildren ( Lamidan, Iodis- Concentrate, etc.); achievement of an efficient control system for iodine contents in the childrens food products and organisms; decrease of the negative consequences of iodine- deficient endemia, health improvement and school results among the schoolchildren. 7Implementation of prevention measures for the endoecological diseases during floods and other calamites Minimization of the harmful effects of floods and other calamities upon the population by the use of health improvement and phyto-food products; dynamic observation of the health of the patients subjected to harmful ecological impact, at the background of the use of universal natural health improving preparations. 8Artificial counterparts of the natural factors of highly mineralized Solotvyno Salt Lake designed for treatment of chronic dermatoses 2011– 2012 Launch of the production of preparations based on halophylic bacteria to improve skin photosensitization by 1.5 times during ultraviolet phototherapy of the patients suffering from psoriasis.

52 Environmental protection and stabilization (Solution of the ecological problems of the Carpathian region) A complex of activities aimed at solution of the problems of the Carpathian region, environmental protection and stabilization, and solution of agricultural problems is to be fulfilled in the following directions: elaboration of decision-making systems for emergency cases of anthropogenic and natural catastrophes; research of the level of pollution of the atmospheric air in urban areas of Transcarpathian region with carcinogenic substances; research of the impact of solid household waste polygons and dumps upon the ecological state of environmental objects; fight with formation of mud streams; improvement of the ecological state of Transcarpathian minor rivers; preservation and recovery of forest zone upper confines і;

53 fight against spread of particularly dangerous non-aboriginal plants; preservation of the gene pool of the Hutsul breed horses; development of horticulture and viticulture. Implementation of the above activities will enable: to substantially enhance public safety in case of emergence and duration of natural flood and mud stream situations; to optimize the anti-flood defence system; to provide for a number of conditions required for permanent nature management; to create the necessary prerequisites for the natural ecosystems return to their initial natural state within the region of the Carpathian Mts. both in Ukraine and neighbouring countries.

54 Projects No.Project titleTerm of fulfillme nt, years Results expected 1Adoption of decision making patterns for anthropogenic and natural disasters 2011– 2016 Increase of the level of trustworthiness and preciseness of the decisions taken to forecast the natural phenomena, viz. floods, hurricanes, etc. 2Fight with formation of mud torrents Development and launch of the systems of fight against emergency cases resulting in formation of mud torrents (a Useful Model Patent issued). 3Development of the method and flowchart for conservation and regeneration of the forest zone upper confines Development, adaptation and launch of the method of raising the upper confines of the forest zone in the Ukrainian Carpathians to strengthen the forests hydrological role and improve regional forestry management.

55 4Study of the pollution level of the atmospheric air in urban areas of Transcarpathian region with carcinogenic substances 2011– 2013 Statistical research of automobile traffic intensity in urban areas of Transcarpathian region, taking into account the fuel and vehicle categories; quantification of vehicle emissions in the urban areas of Transcarpathian region having no stationary observation points (i.e., in all Transcarpathian cities/towns, except for Uzhhorod); estimation of the volumes of vehicle emissions based on international methods and standards; calculations of dangerous substance concentration fields by mathematic modeling methods in the urban areas of Transcarpathian region; identification of mean daily doses of influence (LADD) and carcinogenic risk levels (iCR) for public health in certain cities/towns and rayons of Transcarpathian region. 5Development of an overall flowchart for the fight with the spread of extremely dangerous alien (non-aboriginal) plants Evaluation of the current state of the communities of most dangerous alien (non-aboriginal) plants; an overall flowchart of liquidation of the concentration sites of most dangerous alien (non-aboriginal) plants is to be suggested; recommendations on making further spread of most dangerous alien (non-aboriginal) plants impossible are to be developed and fulfilled.

56 6Evaluation of the resource potential of medicinal plants Study of the biological and use stocks of medicinal plants; Establishment of the limits of laying-in of medicinal plants according to the set standards; Development of cartographic material showing the locations of industrially attractive communities of medicinal plants. 7Preservation of the gene pool of horses of the Hutsul breed by their use at agriculture and forestry, mountain tourism and therapeutic riding (hyppotherapy) Expansion of opportunities of environmentally friendly agricultural production; environmental conservation during logging and agricultural production; rise in efficiency of resort-type treatment (diseases of locomotor apparatus, central nervous system, cardiovascular diseases, diseases of respiratory and digestive systems).

57 8Study of the impact of solid household waste polygons and dumps upon the ecological state of environmental objects Evaluation of the current state of affairs, and data on stockholding of solid household waste in Transcarpathian region; data on the changes in the state of environmental objects affected by the solid household waste polygons and dumps; recommendations on minimization of the impact of the solid household waste polygons upon the ecological state of environmental objects; recommendations on the ways of solution and softening of the issue of solid household waste in Transcarpathian region; calculations of possible biomass emission from the solid household waste polygons and dumps in Transcarpathian region. 9Evaluation of the ecological state of Transcarpathian minor rivers, and identification of its improvement possibilities Data on the real ecological state of Transcarpathian minor rivers; detection of the sources of anthropogenic impact upon the state of minor rivers, and possible ways of its elimination; mapping of the areas of minor rivers, and estimation of their recreation attractiveness; recommendations on improvement of the ecological state of Transcarpathian minor rivers, optimization of human economic activity with regard to their impact upon minor rivers, including that of tourism and recreation.

58 10Production of grape saplings based on the use of Biogumat preparation 2011– 2013 Increase of grape plants survivability as compared with the current technologies; lowering of the products cost price by cutting the power inputs; output of ecologically pure products, and environmental protection by means of application of a natural physiologically active preparation. 11Promising clonal rootstock and varieties for early- maturing pear-tree plantations 2011– 2014 Optimum selection of the clonal rootstock of pear trees adapted to the growth conditions, early-maturing, high- yield variety-rootstock combinations, and main elements of pear crowned saplings growth technology.

59 Debrecen, Hungary, 2008I. Studenyak Thank you for your attention