Modulation of Ras - Signal Transduction. Ras - Raf signal transduction. - презентация

1 Modulation of Ras - Signal Transduction

2 Ras - Raf signal transduction

3 Modulation of Ras - Signal Transduction

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5 Binding study in aqueous buffer pH 7 ITC of Ras Mg 2+ GppNHp and zinc(II)cyclen One site binding model reveals micromolar affinity

6 Spectra recorded at 278 K in aqueous buffer solution R. Kalbitzer, BK, patent R. Kalbitzer, M. Spoerner, T. Graf, BK, Biochem. Biophys. Res. Commun. 2005, 334, P NMR spectra of Ras Mg 2+ GppNHp

7 1.3 mM Ras(wt) with 2.6 mM Cu 2+ - cyclen 1.3 mM Ras(T35A) with 6.5 mM Cu 2+ - cyclen

8 Modulation of Ras - Signal Transduction

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